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trans-1, 4-Dibromo-2-butene

Dadi
821-06-7
Out of stock
$0.00
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1. A Critical Cornerstone of Pharmaceutical Synthesis
   As a core intermediate in the synthesis of the antihypertensive drug aliskiren, its structural specificity enables precise participation in the construction of the drug’s molecular framework, directly affecting the stability of the final product’s efficacy. In the synthesis  of RAAS system inhibitor drugs, it is an irreplaceable key raw material, meeting the pharmaceutical industry’s rigid demand for high-purity intermediates.  
2. Excellent Physicochemical Stability
   It has well-defined melting point (48-53°C) and boiling point (205°C), and exists as stable foliar crystals at room temperature. Its property of being slightly soluble in common organic solvents facilitates storage and stepwise reaction control, reducing loss rates during production and improving synthesis efficiency.  
3. Strong Process Compatibility
   It can be efficiently prepared through the microchannel reaction of 1,3-butadiene and bromine. The reaction conditions (-70~0°C, 1-10 minutes) are easy to scale up industrially, and the product has high purity, which can adapt to continuous production processes and meet the supply demand for large-scale pharmaceutical intermediates.  
4. High Quality Controllability
   With a clear CAS number (821-06-7) and molecular structure (trans configuration), it can be accurately tested for purity by chromatographic methods, complying with the pharmaceutical industry’s strict standards for raw material traceability and quality consistency, and reducing the risk of impurities in downstream drug synthesis.

trans-1, 4-Dibromo-2-butene
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